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Brian D Hammann Selected Research

MZ-J-7-118

4/2007Alterations of EGFR/HER, angiogenesis and apoptosis pathways after therapy with antagonists of growth hormone releasing hormone and bombesin in non-small cell lung cancer.
11/2005Inhibition of human androgen-independent PC-3 and DU-145 prostate cancers by antagonists of bombesin and growth hormone releasing hormone is linked to PKC, MAPK and c-jun intracellular signalling.
8/2005Antagonists of growth hormone releasing hormone (GHRH) and of bombesin/gastrin releasing peptide (BN/GRP) suppress the expression of VEGF, bFGF, and receptors of the EGF/HER family in PC-3 and DU-145 human androgen-independent prostate cancers.

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Brian D Hammann Research Topics

Disease

3Neoplasms (Cancer)
04/2007 - 11/2004
2Prostatic Neoplasms (Prostate Cancer)
11/2005 - 08/2005
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2007
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
11/2004

Drug/Important Bio-Agent (IBA)

4Hca(6)-Leu(13)-psi(CH2N)-Tac(14)- bombesin(6-14)IBA
04/2007 - 11/2004
4BombesinIBA
04/2007 - 11/2004
4Gastrin-Releasing PeptideIBA
04/2007 - 11/2004
4Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)IBA
04/2007 - 11/2004
3MZ-J-7-118IBA
04/2007 - 08/2005
2ErbB Receptors (EGF Receptor)IBA
04/2007 - 08/2005
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2007 - 08/2005
2AndrogensIBA
11/2005 - 08/2005
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
04/2007
1Insulin-Like Growth Factor II (Somatomedin A)IBA
08/2005
1Messenger RNA (mRNA)IBA
08/2005
1Epidermal Growth Factor (EGF)IBA
08/2005
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
08/2005
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2005
1Insulin-Like Growth Factor I (IGF-1)IBA
08/2005
1Protein Kinase CIBA
11/2004
1Protein Isoforms (Isoforms)IBA
11/2004

Therapy/Procedure

1Therapeutics
04/2007